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CJ-13,610 hydrochloride
CAS No. 179420-27-0
CJ-13,610 hydrochloride( —— )
Catalog No. M27863 CAS No. 179420-27-0
CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 88 | Get Quote |
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| 10MG | 152 | Get Quote |
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| 25MG | 336 | Get Quote |
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| 50MG | 500 | Get Quote |
|
| 100MG | 705 | Get Quote |
|
| 500MG | 1485 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCJ-13,610 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionCJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs.
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DescriptionCJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs.(In Vitro):In intact human polymorphonuclear leukocytes (PMNL), challenged with the Ca(2+)-ionophore A23187, CJ-13,610 hydrochloride potently suppressed 5-LOX product formation with an IC50 of 70 nM. In transfected HeLa cells, CJ-13,610 hydrochloride only slightly discriminated between phosphorylatable wild-type 5-LOX and a 5-LOX mutant that lacks phosphorylation sites.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetLipoxygenase
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RecptorSTAT3
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Research Area——
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Indication——
Chemical Information
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CAS Number179420-27-0
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Formula Weight429.96
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Molecular FormulaC22H24ClN3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.O=C(N)C1(C=2C=CC=C(SC3=CC=C(C=C3)N4C=CN=C4C)C2)CCOCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ayyiliath M Sajith, et al. Pyrimidine-2,4-dione targets STAT3 signaling pathway to induce cytotoxicity in hepatocellular carcinoma cells. Bioorg Med Chem Lett. 2021 Oct 15;50:128332.
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